個人簡介
蘇梟，博士👩🏽🍳，中國科沐鸣2特聘研究崗位（二級研究員），博士生導師。2004年獲復旦大學和美國UCSF聯合培養博士學位；2004-2007美國UCSF博士後；2007-2012美國UIC助理研究教授和UCSF副研究員；2012年擔任呼吸道感染免疫課題組組長🤴🏼。主持國家自然基金重點項目🏄💇♂️、重大項目集成重點、重點專項🔛、國家自然基金重大培育和面上項目（多項）🤲🏼；上海市基礎重點⚠；承擔國家重點研發計劃和中國科沐鸣2先導B項目等。現任上海市肺部炎症和損傷重點實驗室副主任🤟、上海市免疫學感染免疫專業委員會委員、牛津大學出版社QJM雜誌（IF14）常務副主編, Mol Med副主編等。在Nature Med、Lancet、JCI、Cell Discovery等雜誌發表論文100多篇🫶🏼，引用率6200多次。
研究方向
肺炎症損傷和修復神經調控機製
感覺神經元識別肺內病原和應答的神經環路
榮譽及獲獎情況
獲得美國Parker B. Francis肺生物醫學獎
美國NIH Ruth L. Kirschstein獎
市級科技進步一等獎等
主持與承擔主要項目情況
Doi: 10.1016/j.virs.2023.05.005
Di CX, Jiang YS, Li LL, Qiu WN, Shi MM, Zhu YG, Zhang J, Song YL, Su X*, Qu JM*. ASCs activate cGAS-type I IFNs-IL-7 axis via Pseudomonas aeruginosa-derived outer membrane vesicles to resolve pneumonia. Stem Cells. 2023, DOI: 10.1093/stmcls/sxad016
Li N, Chen J, Xie S, Zhang M, Shi T, He Y, Jie Z*, Su X*. Oral antibiotics relieve allergic asthma in post-weaning mice via reducing iNKT cells and function of ADRB2. Front Immunol. 2022 Oct 25;13:1024235. doi: 10.3389/fimmu.2022.1024235. eCollection 2022.
Wen J, Zhao C, Chen J, Song S, Lin Z, Xie S, Qi, H Wang J, Su X*. Activation of α7 nicotinic acetylcholine receptor promotes HIV-1 transcription. Cell Insight, 2022 June 2022📍；1 (3): 100028.doi.org/10.1016/j.cellin.2022.100028.
Gao ZW, Li L, Huang YY, Zhao CQ, Xue SJ, Chen J, Yang ZZ, Xu JF*, Su X*. Vagal-α7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection. Acta Pharmacol Sin. 2021 Jan 7. doi: 10.1038/s41401-020-00579-z.
Feng XT, Zhao CQ, Li L, Feng JJ, He W, Shi TY, Li N, Jie ZJ*, Su X*. iNKT cells with high PLZF expression are recruited into the lung via CCL21-CCR7 signaling to facilitate the development of asthma tolerance in mice.Eur J Immunol. 2020 Jul 26. doi: 10.1002/eji.202048798.
Chen XY, Zhao CQ, Zhang CP, Li QM, Chen J, Cheng LP, Zhou J, Su X*, Song YL* Vagal-α7nAChR signaling promotes lung stem cell regeneration via fibroblast growth factor 10 during lung injury repair.Stem Cell Res Ther. 2020 Jun 10;11(1):230. doi: 10.1186/s13287-020-01757-w.
Chen XY, Chen J, Song YL*, Su X*. Vagal α7nAChR signaling regulates α7nAChR+Sca1+ cells during lung injury repair.Stem Cell Res Ther. 2020 Aug 31;11(1):375. doi: 10.1186/s13287-020-01892-4.
Zhang H, Xue K, Li W, Yang X, Gou Y, Su X, Qian F, Sun L. Cullin5 drives experimental asthma exacerbations by modulating alveolar macrophage antiviral immunity. Nat Commun. 2024 Jan 4;15(1):252. doi: 10.1038/s41467-023-44168-0
Li Y, Lu Y, Lin SH, Li N, Han Y, Huang Q, Zhao Y, Xie F, Guo Y, Deng B, Tsun A, Du J, Li D, Sun J, Shi G, Zheng F, Su X, Duan S, Zheng SG, Wang G, Tong X, Li B. Insulin signaling establishes a developmental trajectory of adipose regulatory T cells. Nat Immunol. 2021 Aug 24. doi: 10.1038/s41590-021-01010-3.
聯系方式
Email💃🏿：xsu@siii.cas.cn
辦公地址：上海市嶽陽路320生命科學研究大樓B609